exploit knowledge of the fundamental principles of molecular biology to analyze contributions of DNA and proteins to human physiology and behavior
identify, select, and query the appropriate database to best answer the bioinformatics question at hand, and effectively and accurately interpret the outcome
For the protein annotation project, you will use the protein coded by the gene in the gene annotation project, if it was noncoding gene, choose any protein of interest to annotate. The following tasks must be completed and must provide screenshots
Provide the protein sequence from the provided gene sequence and state protein name, gene name and amino acid length. Include accession ID or protein ID from UniProt, or NCBI
identify the protein function
protein family, conserved domains: name and location by amino acid number
gene ontology (GO): Provide 2 GOs per each one of these sections where available. Sections: Molecular function, Biological process and cellar component. Include GO ID, name, and definition
computational analysis of protein-protein interactions: total number of interactors and at least three names and protein ids of the interactors where available, if there is none, choose 3 other unique features of your protein not on the list
Do not cut and paste your database results to report your findings. Write two to three paragraphs reporting the information you have obtained about this protein. Imagine this is a report you will present to an employer or a group of researchers interested in this protein.
Content
Excellent
Very Good
Good
Fair
Poor
Points
4
3
2
1
0
Protein Identification
correct identification of protein name, gene name, sequence, protein id and amino acid length
correctly identifies at least three of the listed features
correctly identifies at least two of the listed features.
Wrong identification of all the listed features
no answer
Protein Function
All functions
most functions
Some functions
Wrong protein function identification
no answer
Family and Domain information
Correct protein family, conserved domain names, amino acid location
Correctly identifies two of the three required features
Correctly identifies one of the required three features
Wrong identification for all
no answer
Gene ontology information
Have correct six GO terms in three sections including id name and definition
Have correct six Go terms in the three sections but is missing the required description
Have no fewer than three correct GO terms with some description
Have fewer than three correct GO terms
no answer
Protein protein interactions
Correctly Identifies all the three interactors with protein names and ids
Correctly identifies fewer three interactors but has the names and protein ids
Correctly identifies all the three interactors with missing names and ids
Identifies fewer than three interactors with no names and ids
No answer
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